Skip To The Main Content

Browse these ideas available for licensing that have the potential to improve lives while creating jobs to support and grow the region.

All technologies
 are listed as non-confidential technical summaries.

Technologies were generated by academic institutions, entrepreneurs, and corporations.

Click the Tech Search button below to have Whiteboard2Boardroom staff complete a personalized search for innovations to license from our research institution partners.

The most recent innovations from our partners are featured separately and organized by category. All listings are updated as new technology opportunities become available. 

For assistance in connecting with, or attaining further information on any of these technologies, please contact us.

New Liposomes for Delivery of Cancer Treatments

Researchers at Kansas State University have successfully created more effective liposomes with better encapsulation, targeting and delivery capabilities through protease sensitive copolymer encapsulation for delivery of anti-cancer therapeutics. Their selective liposomes have a covalently bound polymer cage, which prevents premature leakage of contents, in combination with cholesterol-derived protease sensitivity. Studies indicate that this new technology may potentially have an exponentially longer shelf-life, will allow for specific targeting of cancer cells, as well as other malignant cells, and rapid delivery of all contents within the liposome upon contact with cancer-specific proteases. Since the proteases that activate the release of the liposomes’ contents only exist in the presence of cancer cells, very little if any immune response should occur nor will cancer cells have time to build up defense to the killing agent.

Of the numerous cancer treatment techniques, liposome drug delivery has been at the forefront of discussion over the past decade, due to its versatility and ability to deliver drugs for not only cancer treatment, but also treatment of other diseases or ailments. However, despite great promise, the use of liposomes in treating cancer has been severely limited by their short shelf-life, inability to contain cancer-killing agents without leaking, and lack of mechanisms to release all contents rapidly upon contact with cancer cells.

-Typical liposome shelf-life is 1-2 weeks, whereas these liposomes may last 3-12 months
-The protease sensitive polymer cage prevents leakage and increases selectivity
-High sensitivity to cancer-proteases allows liposome contents to be released rapidly
-These liposomes can be used to target cancer and other diseases
-Costs will be similar to pre-existing, less effective analogues

-Treatment of cancerous tumors or other concentrated malignant cells
-Targeted treatment of other diseases or conditions that involve signature proteins or cells that can be “painted” and attacked
-Extended shelf-life would allow for storage and shipment, potentially opening new global markets

-US Patent Application #13/800,456 filed on March 13, 2013

Additional Details


Kansas State University

Intellectual Property Protection

Patent Issued

Interested? Request More Information