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Flexible Microfluidic Interfaces for Drug Discovery and Disease Diagnosis

Interfaces play vital roles in the integration of microfluidic systems. Miniaturization of microfluidic systems offers numerous benefits including reduced consumption of reagents, accelerated analysis speed and simplified automation. However, various microfluidic modules desire convenient and robust interfaces for connections. Poly(dimethylsiloxane), or PDMS, is a popular material for prototyping of microfluidic devices. The basic principle is based on the flexibility and in-situ consolidation property of PDMS. This fabrication largely depends on the mold fabrication methods. By using PDMS, WSU researchers developed a simple method to fabricate interfaces for connecting microfluidic modules: capillary to capillary, capillary to needle, multiple-way mixers and flow gates. Our interfaces can be applied to capillary electrophoresis systems, microfluidic systems and other capillary-connection involved systems.


-Easy to connect
-Convenient for visual trouble shooting
-Easily mass-produced
-Saves time and effort
-Flow gates reduce volumes of buffer consumption

-Drug discovery, quality control, disease diagnosis, routine checkup

Additional Details


Wichita State University

Intellectual Property Protection

Pending Patent

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