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Carbon Foam as a Bone Graft Substitute

Particulate materials derived from controlled breakage of vitreous carbon foam constructs have been developed as a platform technology for multiple medical procedures performed to address diverse tissue deficits and/or pathologies. The results of these studies have revealed that particulate vitreous carbon foam-derived particles are biocompatible, permissive of cell attachment and differentiation, bind regenerative-important growth factors in an active elutable form, and provide a 3-dimensional substrate that encourages rapid neo-vascularization and bone formation. These materials can be formulated into flowable gels, putties and granules, enabling them to be used in a multitude of clinical applications.

BENEFITS:
-Improved binding, retention, and delivery of drugs and cytokines
-Increased surgical options without the need to harvest bone for grafting procedures
-Effective bone formation with significantly reduced biological response modifier dosage
-Flowable configuration increases surgical handling options
-Reduced out-of-pocket expense as compared to other osteoinductive bone graft substitute products
-Potential decrease in off-target side effects of therapeutic agents

APPLICATIONS:
-Spinal fusion
-General orthopedics
-Vertebroplasty
-Wound care
-Oral and maxillofacial surgery

Additional Details

Owner

Wichita State University

Intellectual Property Protection

Pending Patent



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