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Biosensors for Detecting Macromolecules and Other Analytes

Researchers have developed molecular biosensors, methods, and kits for detecting severaltypes of target molecules including polypeptides, analytes, macromolecular complexes, and combinations thereof. These methods are well adapted to rapid, high-throughput parallel protein detection.

BACKGROUND:
The detection, identification, and quantification of specific molecules in our environment, food supply, water supply, and biological samples (e.g., blood, cerebral spinal fluid, urine, etc.) can be very complex, expensive, and time consuming. Methods utilized for detection of these molecules include gas chromatography, mass spectroscopy, DNA sequencing, immunoassays, cell-based assays, biomolecular blots and gels, and numerous other multi-step chemical and physical assays. There continues to be a high demand for convenient methodologies for detecting and measuring the levels of specific proteins in biological and environmental samples.

BENEFITS:
The potential benefits of this technology include:
  • Minimize the complexity of detecting, identifying, and quantifying specific molecules
  • Minimize the cost of detecting, identifying, and quantifying specific molecules
  • Minimize the time required for detecting, identifying, and quantifying specific molecules

APPLICATIONS:
This technology has several potential applications including:
  • Biomedical research
  • DNA sequencing
  • Immunoassays and cell-based assays
  • Multi-step chemical and physical assays


Additional Details

Owner

Saint Louis University

Intellectual Property Protection

Patent Issued



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