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Method for Improved Efficiency in Cloning Pigs

The current invention developed by researchers at the University of Missouri is an improved method for increasing the efficiency of cloning pigs. This method improves the efficiency of oocyte activation with unfertilized mammalian oocyte and is less time consuming than the current method used in the industry.

This is a novel method to activate reconstructed pig embryos. Unlike other methods available, this new approach does not fully rely on calcium signal to activate reconstructed embryos. By chemically stimulating the downstream pathway of calcium signaling, reconstructed pig embryos can be successfully activated. In addition, the procedure is simple and user friendly. This method may benefit the genetically-engineered pig industry by increasing the efficiency and success in generating genetically modified pigs at reduced costs.

POTENTIAL AREAS OF APPLICATIONS:
Genetically-engineered pigs:
-to provide human compatible cells, tissues, and organs for the treatment of human diseases
-to produce tissues for human transplant surgeries
-for medical and veterinary research
-to increase production of porcine-derived food products

MAIN ADVANTAGES OF INVENTION:
-Inexpensive in comparison to current techniques in the industry
-Time savings process to produce piglets
-Potential greater efficient in generating cloned pigs in comparison to current methodologies

STATE OF DEVELOPMENT:
-On-going, healthy piglets have been produced using this technology

Additional Details

Owner

University of Missouri

Intellectual Property Protection

Pending Patent



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